Watch Powerpuff Girls videos and see three super-powered little girls save the world before bedtime. Created by Professor Utonium when he mixed Chemical X with some sugar and spice, the Powerpuff Girls protect Townsville from bad guys and villains like Mojo Jojo, Fuzzy Lumpkins, Him, Princess, the Gangreen Gang and others. Blossom is the commander and the leader. Bubbles is the joy and laughter. Buttercup is the toughest fighter. And together, the Powerpuffs save the day! Watch free online videos from The Powerpuff Girls on Cartoon Network.